What significance do the Tuskegee Syphilis Study, American Indian Community, and Belmont Report have to the history of historical trauma and medical mistrust?

ResearchEthics– Read Chapter 6 and article on Redressing Past Wrongs “Cottrell, R., Mckenzie, J. (2011). Health promotion education research methods: Using the five-chapter thesis/dissertation model (2nd edition). Sudbury, MA: Jones and Bartlett Learning. ”
After reading the article of Breaking the Cycle of Mistrust (attached) What ethical violations did the researchers commit regarding a) consent, b) trust, debriefing (also known as dehoaxing, and c) confidentiality?
What significance do the Tuskegee Syphilis Study, American Indian Community, and Belmont Report have to the history of historical trauma and medical mistrust?